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ea0022p261 | Developmental endocrinology | ECE2010

An inadequate maternal dietary protein level during pregnancy in pigs alters the expression of corticosteroid receptors and 11β-hydroxysteroid dehydrogenase isoforms in the placenta and fetal brain

Kanitz Ellen , Grabner Maria , Tuchscherer Margret , Brussow Klaus-Peter , Stabenow Bernd , Rehfeldt Charlotte , Metges Cornelia C , Otten Winfried

Imbalanced maternal nutrition during pregnancy can cause fetal growth retardation, metabolic changes and alterations of the hypothalamic–pituitary–adrenal (HPA) system in the offspring. Here, we investigated the effects of maternal low and high protein diets during pregnancy in pigs on materno-fetal HPA regulation and expression of glucocorticoid receptor (GR), mineralocorticoid receptor (MR), 11β-hydroxysteroid dehydrogenase 1 and 2 (11β-HSD1 and 11β-...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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